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TriVersa NanoMate®

Nanoelectrospray ionization technology

The TriVersa NanoMate LESA® is the latest in chip-based electrospray ionization technology from Advion. It combines the benefits of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated ion source platform.

Obtain more information from complex samples than LC/MS alone

The TriVersa NanoMate® integrates with:

  • Advion ESI Chip®
  • LC/MS with Fraction Collection for Re-Analysis by Infusion
  • Liquid Extraction Surface Analysis (LESA® and LESAplus)

Advion ESI Chip®

The ESI Chip® unleashes the power of mass spectrometry through miniaturization. This microfluidics chip contains an array of 400 nano-electrospray nozzles, etched in a silicon wafer. The fabrication method is highly reproducible to ensure the integrity and equal performance of each nozzle. The electrical field created by the nano-electrospray nozzles results in a highly efficient ionization and long-lasting, stable spray from µL of sample volume.

  • ESI chips are available in three different nozzle emitter sizes from 2.5 µm to 5.5 µm ID
  • Internal chip void volume in the pL range allows for 15 min spray times from only 3 µL of sample
  • Automated sample handling can deliver spray from samples in 96 or 384 well plates
  • Silicon chip design delivers superior electric field strength and ionization efficiency
  • Internal counter electrode allows for spray sensing and recovery feature


Chip-based Direct Infusion and LC/MS Fraction Collection with Re-analysis by Infusion

Liquid Extraction Surface Analysis (LESA® and LESAplus)

Liquid Extraction Surface Analysis


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